GMHA Modeling Analysis

Global Aging Among
People Living with HIV

As antiretroviral therapy (ART) continues to extend life expectancy, the global population of people living with HIV (PWH) is aging rapidly. This demographic shift has important implications for healthcare systems worldwide, particularly in sub-Saharan Africa, where the burden of HIV remains highest.

The Global Model of HIV & Aging (GMHA) is a compartmental model of HIV transmission, treatment, and population aging that provides a robust framework for studying demographic trends among PWH. Originally developed to characterize HIV and aging dynamics at a broad scale, the model has been adapted and expanded to represent nine individual countries that collectively account for approximately 50% of the global population living with HIV, as well as four income-group aggregates and a global model. These extensions enable comparative analyses of aging trends across diverse epidemiological and socioeconomic settings.

This interactive tool explores projected age distributions of PWH from 2025 to 2040 across multiple locations. Projections can be viewed as either counts or proportions for the overall population and stratified by age groups. The lower panels provide a brief description of modeling methodology and a summary review of model calibration for each location.

Upcoming

GMHA at AIDS 2026

Rio de Janeiro · 26th International AIDS Conference

  • Satellite session
    Tue, Jul 28 · 6:00–7:30 pm
    Report from The Lancet HIV commission on HIV and ageing
  • Poster presentation
    Tue, Jul 28 · 12:00–1:00 pm
    Forecasting the Global Age Distribution of People with HIV from 2025–2040
  • Poster presentation
    Wed, Jul 29 · 12:00–1:00 pm
    The potential impact of long-acting injectable ART to reduce HIV incidence among youth in South Africa
Conference details

About these plots: These plots display the model-projected age distributions (both as total counts and relative percentages by age) of people living with HIV in each location over time.