GMHA Modeling Analysis
Global Aging Among
People Living with HIV
As antiretroviral therapy (ART) continues to extend life expectancy, the global population of people living with HIV (PWH) is aging rapidly. This demographic shift has important implications for healthcare systems worldwide, particularly in sub-Saharan Africa, where the burden of HIV remains highest.
The Global Model of HIV & Aging (GMHA) is a compartmental model of HIV transmission, treatment, and population aging that provides a robust framework for studying demographic trends among PWH. Originally developed to characterize HIV and aging dynamics at a broad scale, the model has been adapted and expanded to represent nine individual countries that collectively account for approximately 50% of the global population living with HIV, as well as four income-group aggregates and a global model. These extensions enable comparative analyses of aging trends across diverse epidemiological and socioeconomic settings.
This interactive tool explores projected age distributions of PWH from 2025 to 2040 across multiple locations. Projections can be viewed as either counts or proportions for the overall population and stratified by age groups. The lower panels provide a brief description of modeling methodology and a summary review of model calibration for each location.
Upcoming
GMHA at AIDS 2026
Rio de Janeiro · 26th International AIDS Conference
- Satellite sessionTue, Jul 28 · 6:00–7:30 pmReport from The Lancet HIV commission on HIV and ageing
- Poster presentationTue, Jul 28 · 12:00–1:00 pmForecasting the Global Age Distribution of People with HIV from 2025–2040
- Poster presentationWed, Jul 29 · 12:00–1:00 pmThe potential impact of long-acting injectable ART to reduce HIV incidence among youth in South Africa
About these plots: These plots display the model-projected age distributions (both as total counts and relative percentages by age) of people living with HIV in each location over time.